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Levels co-founder Casey Means tapped for surgeon general Read in browser
Endpoints News
Thursday, 8 May 2025
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Longevity goes mainstream
The pursuit of longevity isn’t just for Silicon Valley biohackers anymore.
Hims & Hers is likely to see a dent in its revenue from new limits on compounded weight loss drugs, so it’s searching for the next big product that'll drive its growth.
On Monday, when Hims announced first-quarter earnings, CEO Andrew Dudum said he’s eyeing long term opportunities in “longevity, sleep and preventative care.” He also gushed about peptide innovation and the prospect of bringing it to the masses. (Peptides have grown popular in the biohacking and anti-aging communities, but the regulation behind much of the category is lacking.) 
“You're going to start seeing offerings in the next couple of years that are more about gaining understandings of your health and taking that first step to be the most optimized you can for not only yourself, but also your family,” Dudum said.
He added later in the call that he anticipates a mass market in the next two to five years for whole body testing and scans, and polygenic risk scores for chronic conditions like Alzheimer’s disease at affordable prices that allow people to collect this information on an annual basis and shore up the body with vitamins and prescription medications.
There are a growing number of venture-backed startups trying to make this vision a reality. Earlier this week, buzzy lab testing company Function Health bought Ezra, a whole body MRI company, and the two said they’re lowering the cost of preventive scans to $499 from thousands of dollars. And a couple of weeks ago, Function competitor Superpower raised $30 million.
For Hims, moving into this realm would mark somewhat of a strategy shift: Most of the drugs it prescribes are aimed at fixing existing conditions that patients have self-diagnosed. Leaning into longevity and prevention would position it to help patients uncover conditions they’re at risk for or didn’t know they had. It also further aligns the startup with the Make America Healthy Again ethos (HHS Secretary Robert F. Kennedy Jr. is big on peptides, apparently!).
But I’m not convinced longevity products will drive the explosive growth companies have seen from GLP-1 weight loss drugs. Elective testing and scans are expensive, and they’re rarely covered by insurance for preventive reasons. Plus, the evidence behind their use, and that of plenty of longevity/wellness products like certain supplements and popular peptides, is dubious. 
Weight loss drugs might not be cheap either, but there was never doubt that they work. It’s that plain-to-see efficacy that was enough to convince millions to hand over their cash. 
- Shelby 
Here’s what’s new
Compounders just lost their case to put obesity drug tirzepatide back in shortage
A fed­er­al court hand­ed the FDA and Eli Lil­ly a ma­jor win in a case chal­leng­ing the end of the tirzepatide short­age.
Cedars-Sinai partners with Redesign Health to build health tech startups
Los An­ge­les-based health sys­tem Cedars-Sinai is part­ner­ing with ven­ture stu­dio Re­design Health to build health tech star­tups from scratch, among oth­er ini­tia­tives.
Novo Nordisk trims growth forecast as GLP-1 compounder ban yet to go live
No­vo Nordisk said on Wednes­day that com­pound­ing phar­ma­cies’ pro­duc­tion of its GLP-1 med­i­cine semaglu­tide had re­duced its mar­ket pen­e­tra­tion more dra­mat­i­cal­ly than it had ex­pect­ed — caus­ing it to cut its full-year rev­enue guid­ance by about three per­cent­age points.
Quote of the week
"It's their choice. It's not really something we have a say in."
Novo Nordisk CEO Lars Fruergaard Jørgensen said of Wegovy's preferred placement on CVS Health’s formulary
This week in health Тech
President Donald Trump picked Casey Means to be the next US surgeon general. Means is the co-founder of Levels Health, a startup that combines an app and continuous glucose monitors. She’s been critical of the pharmaceutical industry and has questioned the safety of vaccines. “Casey has impeccable ‘MAHA’ credentials,” Trump said on Truth Social.
Hinge Health updated its S-1 filing on Monday, sharing the results from its first quarter of 2025. The company made $124 million in revenue in the first quarter and posted a quarterly profit of $17 million.
Glenview cut its stake in CVS after the pharmacy giant’s first-quarter earnings, citing “healthy” results and CVS’ increase to its annual guidance. Glenview first took a stake in CVS in May 2024. In the time since, the investor brought in new board members and supported CVS replacing Karen Lynch with David Joyner as CEO.
Oscar Health posted earnings on Wednesday morning that beat Wall Street expectations. The insurer reported a net income of $275 million on $3 billion in revenue. In its earnings call, CEO Mark Bertolini noted the company’s overlap in coverage with Aetna, which is leaving the Affordable Care Act marketplace in 2026, saying he viewed the departure as an opportunity for Oscar. The stock closed Wednesday up about 30%.
WeightWatchers officially filed for bankruptcy on Tuesday. It’s an attempt for the longtime weight loss company to get rid of its debt as it faces increased competition. Sima Sistani, former WeightWatchers CEO, said in a LinkedIn post that the proceedings are “good news for their ability to invest in the future of the product and their beautiful community.”
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